Regenerative Medicine at UPC · Riverside & Menifee, CA
IV Lidocaine Infusion for Chronic Pain
A gentle, closely monitored, non-opioid IV treatment that may help quiet overactive pain nerves — for nerve pain, CRPS, fibromyalgia and other chronic pain that hasn't responded to other care.
Medically reviewed by Rainier Guiang, MD · Board-certified in Anesthesiology and Pain Management (ABA)

What Is an IV Lidocaine Infusion?
Lidocaine is a local anesthetic — the same family of medicine used to numb skin before a procedure. In an IV lidocaine infusion, a low dose is given slowly through a small IV while you relax in a comfortable chair and our team monitors you throughout.
Instead of numbing one spot, the infusion reaches nerves throughout the body. It is used for chronic pain driven by overactive or sensitized nerves — pain that often doesn't respond well to standard pain pills, and for which many patients want a non-opioid option.
Every plan starts with a consultation with Dr. Guiang, who reviews your diagnosis, history and current medications to decide whether lidocaine is a safe, reasonable choice for you. It's one of several physician-administered IV infusions for pain we offer, alongside IV ketamine for chronic pain.
Turning Down the Pain “Volume”
Nerves send pain signals by opening tiny sodium channels — the “switches” that let a signal fire. In chronic nerve pain, those switches can fire too easily and too often.
Overactive nerves misfire
Sensitized pain nerves fire again and again, keeping pain “switched on” long after an injury or illness.
Lidocaine blocks sodium channels
The slow infusion settles into those overactive switches, making it harder for pain nerves to keep firing.
Calmer pain signals
With fewer misfires, pain signals may quiet down. For some patients the effect lasts well beyond the infusion itself.
A Calm, Closely Monitored Visit
Non-opioid option
No opioids, no surgery and no incisions — just a small IV.
About 30–60 minutes
Relax in a comfortable chair while the infusion runs slowly.
Monitored throughout
Physician-supervised, with continuous cardiac monitoring start to finish.
Relief may last weeks
For some patients — responses vary, and some people don't respond.
1 · Check-in & screening
We review your health, medications and vital signs.
2 · Monitors on
A small IV is placed and cardiac monitoring begins.
3 · 30–60 min infusion
The lidocaine runs slowly while you rest and we watch closely.
4 · Brief observation
A short check afterward, then home with aftercare guidance.
Conditions It May Help
IV lidocaine is most often considered for pain that comes from the nerves or a sensitized nervous system — especially when other treatments haven't helped enough.
Not sure if your pain fits? Book a consultation — Dr. Guiang evaluates every patient individually before treatment.
Is IV Lidocaine Right for You?
Lidocaine infusion isn't right for everyone. We screen every patient first and supervise every infusion closely.
Who should not have itContraindications & cautions
- Allergy to lidocaine or amide local anesthetics
- Heart block (2nd or 3rd degree) or significant arrhythmia
- Severe heart failure or a recent heart attack
- Severe liver disease
- Uncontrolled seizure disorder
- Pregnancy or breastfeeding Discuss
- Certain antiarrhythmics or sodium-channel-blocking drugs Discuss
Your safety comes first
Three safeguards on every lidocaine infusion:
- About 30–60 minutes, physician-supervised
- Continuous cardiac monitoring during every infusion
- Riverside or Menifee office
Simple, Upfront Pricing
Cash-pay clinic · we do not accept insuranceIV lidocaine infusions are $350 per infusion. Your treatment plan is confirmed at your consultation before any treatment, and we can provide a receipt you may submit for possible reimbursement. Questions? Call 951-900-3253.
Meet Dr. Rainier Guiang, MD
Rainier Guiang, MD
Director of Regenerative Medicine · University Pain Consultants
Dr. Guiang is board-certified in Anesthesiology and Pain Management (ABA) and leads the Regenerative Medicine program at University Pain Consultants. He personally evaluates every infusion candidate, reviewing your diagnosis, medications and goals to decide whether IV lidocaine fits into a safe, individualized, non-opioid pain plan.
Locations
Related Non-Opioid Pain Treatments
IV Lidocaine — Frequently Asked Questions
How long does relief from an IV lidocaine infusion last?
It varies from person to person. Some patients notice relief that lasts for weeks after an infusion, others get a shorter benefit, and some do not respond. Results vary, and Dr. Guiang will set realistic expectations at your consultation.
How many lidocaine infusions will I need?
Many patients start with a single infusion to see how they respond. If it helps, repeat infusions may be scheduled at intervals based on how long your relief lasts. Your plan is individualized.
Is IV lidocaine an opioid?
No. Lidocaine is a local anesthetic — the same family of medicine used to numb skin. It is a non-opioid option for chronic and nerve pain.
What side effects can happen during a lidocaine infusion?
Some patients notice mild, temporary lightheadedness, tingling around the mouth or a metallic taste. Tell the team right away — the infusion can be slowed or stopped, and these sensations usually fade.
Is IV lidocaine infusion safe?
Every infusion is physician-supervised, continuous cardiac monitoring is required during every infusion, and your health history and medications are screened first. It isn't right for everyone, which is why a consultation always comes first.
How much does an IV lidocaine infusion cost?
An IV lidocaine infusion is $350 per infusion. Your treatment plan is confirmed at your consultation. See how booking works.
Do you take insurance for lidocaine infusions?
No. Regenerative Medicine at UPC is a cash-pay clinic and does not accept insurance for this service. We can provide a receipt you may submit for possible reimbursement.
How should I prepare for my lidocaine infusion?
Bring a full list of your medications, eat a light meal and drink water beforehand, wear comfortable clothing, and plan to have someone drive you home after your first infusion. Don't stop any medication unless your physician tells you to.