Regenerative Medicine at UPC · Riverside & Menifee, CA
PRP for Sacroiliac (SI) Joint Pain in Riverside & Menifee
Platelet-rich plasma (PRP) from your own blood, considered for sacroiliac (SI) joint pain — one-sided low back and buttock pain that flares with sitting, stairs or rolling over in bed — without jumping straight to surgery.
Medically reviewed by Rainier Guiang, MD · Board-certified in Anesthesiology and Pain Management (ABA)

Is PRP Right for Your SI Joint?
If one-sided low back or buttock pain flares when you stand up, climb stairs, or roll over in bed, platelet-rich plasma (PRP) is one option we use to support joint comfort and function — without jumping straight to surgery.
At Regenerative Medicine at UPC, Dr. Rainier Guiang, MD evaluates whether PRP is a good fit for your SI joint and goals in a focused cash-pay consult.
Who This Is For
PRP for the SI joint is most often considered for:
SI joint dysfunction
Low back and buttock pain below the belt line, often on one side.
Persistent SI pain
Pain that continues after PT, a belt, or a cortisone shot.
Ligament strain after pregnancy or a fall
Considered for loose or irritated SI ligaments.Your exam and imaging guide the plan.
Hoping to avoid SI fusion surgery
Results vary; not a guarantee.
Active adults
Who want a non-opioid, procedure-based option.
Want a candid answer
A focused cash-pay consult with Dr. Guiang on whether PRP fits your SI joint and goals.
Who May Not Be a Good Candidate
PRP may not be right if you haveWe’ll tell you if that’s you
- Inflammatory arthritis that needs rheumatology care first
- Active infection or certain blood disorders
- Unrealistic expectation of a permanent “cure” from one injection
- New weakness, numbness, or bowel or bladder changes Urgent evaluation Surgical opinion
Why patients choose UPC
A physician-led, straight-talking approach:
What PRP Is
PRP uses a concentrated portion of your own platelets, prepared from a blood draw, and injected into the SI joint under appropriate guidance.
Small blood draw
A sample of your own blood is drawn at your procedure visit.
Platelets concentrated
Your blood is processed with the EmCyte PurePRP® system to concentrate the platelets.
Injected into the SI joint
Platelets release growth factors that can support the local healing environment. Results vary.
PRP vs Cortisone for the SI Joint
Cortisone
- Can calm a flare quickly for some people
- Relief is often shorter-lived
- Repeated steroids may not be ideal for ligaments or bone health over time
PRP
- Uses your own platelets — not a steroid
- Chosen more often when the goal is longer-term comfort and function
- Results vary by person and severity
How Long Does PRP Last?
Study results vary by protocol and severity. Many patients who respond notice meaningful change over weeks, with benefit that can last months — Many patients who respond notice gradual change over weeks — published data for SI PRP is still developing, so we set expectations case by case.
*Results vary.
Get a straight answer for your SI joint
Focused, cash-pay consult with Dr. Guiang.
What to Expect
Consult
History, exam, imaging review if available, candid recommendation.
Cash-pay · call for pricingProcedure visit
Blood draw, processing, SI joint injection.
Aftercare
Activity pacing; avoid anti-inflammatories if we ask you to; follow-up plan.
Meet Dr. Rainier Guiang, MD
Rainier Guiang, MD
Director of Regenerative Medicine · University Pain Consultants
Dr. Guiang is board-certified in Anesthesiology and Pain Management (ABA) and leads the Regenerative Medicine program at University Pain Consultants. He evaluates whether PRP is a good fit for your SI joint and goals, and he’ll be direct if it’s unlikely to help.
Locations
Riverside and Menifee, CA — Regenerative Medicine at UPC (University Pain Consultants campus). Regen line: 951-900-3253.
PRP for the SI Joint — FAQ
Is this the same as the insurance pain clinic?
No. Regenerative Medicine at UPC is our cash-pay regenerative department. Traditional insurance-based pain care is separate (University Pain Consultants main line: 951-784-7111).
How do I know my pain is from the SI joint?
SI pain is usually one-sided, below the belt line, and worse with certain movements. Dr. Guiang uses a focused exam and imaging review, and sometimes a diagnostic injection.
Is SI joint PRP physician-performed?
Yes. SI joint PRP injections are physician-performed under appropriate image guidance after an evaluation with Dr. Guiang.
Can PRP help SI pain after pregnancy?
It may help some people with persistent SI ligament pain after pregnancy, once breastfeeding and other factors are reviewed. Results vary.
How much does SI joint PRP cost?
PRP is elective and cash-pay. Call 951-900-3253 for pricing; superbill available on request.