Regenerative Medicine at UPC · Riverside & Menifee, CA
PRP Epidural Injections for Sciatica & Chronic Low Back Pain
A non-steroid option that uses platelet-rich plasma (PRP) from your own blood, placed with image guidance into the epidural space near irritated nerves — performed personally by a board-certified pain physician.
Medically reviewed by Rainier Guiang, MD · Board-certified in Anesthesiology and Pain Management (ABA)
Is a PRP Epidural Right for You?
It may be worth discussing if you live with one of these conditions. Dr. Guiang confirms the cause of your pain first.
Sciatica
Burning, shooting or electric pain that travels from the low back or buttock down the leg.
Disc-related leg pain
Leg pain, numbness or tingling linked to a bulging or herniated lumbar disc irritating a nerve root.
Chronic low back pain
Long-standing low back pain that has not settled with rest, therapy or medications.
Three Steps, One Visit
Blood draw
We take a small sample of your own blood, much like a routine lab draw.
Centrifuge
The sample is spun with the EmCyte PurePRP® system to concentrate the platelets.
Image-guided placement
Dr. Guiang places the PRP into the epidural space near the irritated nerves using image guidance.
Good to know: PRP epidural injection is not FDA approved for back pain or sciatica and research is still evolving. Results vary.
Ready to talk about your back or leg pain?
Call our team or request a consultation at either office.
See the Process
A short look at how a PRP epidural is prepared and performed.
Watch: PRP vs Cortisone Epidural for Sciatica
Why See Dr. Guiang?
Rainier Guiang, MD
Board-certified in Anesthesiology and Pain Management (ABA)
Dr. Guiang holds dual board certifications from the American Board of Anesthesiology in both Anesthesiology and Pain Medicine, and performs every PRP epidural himself. He reviews your exam and imaging first and tells you honestly if PRP isn’t the right fit.
Riverside & Menifee Locations
What Patients Say on Google
“The procedure went well. Immediately after injection my back felt some relief. Its wonderful to have this relief after 6years of feeling pain. I would definitely endorse him to do this procedure again.”
“This was a godsend. I was having back troubles for the past few years and I’ve tried everything from physical therapy to peptides nothing really worked until I got the PRP shot. I’m over a month in and feel like my back…”
“I had an amazing experience with Dr.Guiang and my PRP (platelet-rich plasma) injection for my knee! I had the procedure done on July 1st, and I’m so happy with the results. I had zero pain afterward and have been feeling amazing ever…”
Individual experiences; results vary.
PRP Epidural FAQ
What is a PRP epidural injection?
It is an injection of platelet-rich plasma (PRP), prepared from a small sample of your own blood, placed with image guidance into the epidural space near irritated spinal nerve roots. It is being studied as an alternative to steroid epidurals for sciatica and disc-related back and leg pain. Results vary.
Who may be a candidate?
Adults with sciatica, disc-related leg pain (such as from a bulging or herniated disc), or chronic low back pain who want to explore a non-steroid option. Dr. Guiang reviews your history, exam and imaging first and will tell you honestly if PRP is not a good fit.
How is the procedure done?
We draw a small amount of your blood, concentrate the platelets with the EmCyte PurePRP® system, and Dr. Guiang then places the PRP into the epidural space using image guidance. The visit typically takes about one to two hours, including preparation and observation.
Is a PRP epidural FDA approved?
No. The PRP preparation system is FDA-cleared for preparing PRP, but PRP epidural injection for back pain or sciatica is not an FDA-approved treatment. It is offered as a physician-directed, off-label option, and research is still evolving.
What results can I expect?
Results vary from person to person. Some patients report less leg and back pain over the following weeks, while others notice little change. We cannot promise a specific outcome, and we will discuss realistic expectations at your consultation.
Is it covered by insurance? How much does it cost?
PRP epidural injections are cash-pay and are not covered by insurance. HSA and FSA cards are accepted. Please call 951-900-3253 for pricing.
