Regenerative Medicine at UPC · Riverside & Menifee, CA

PRP for Knee Pain in Riverside & Menifee

Platelet-rich plasma (PRP) from your own blood, considered for knee arthritis, wear-and-tear knee pain and meniscus tears — to support joint comfort and function without jumping straight to surgery.

Your own platelets Not a steroid Non-opioid No surgery

Medically reviewed by Rainier Guiang, MD · Board-certified in Anesthesiology and Pain Management (ABA)

Man holding his painful knee on a park bench
Physician-performed From your own blood Non-opioid option Cash-pay · superbill available

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Save 10% on your PRP injection with code PRP10. Enter the code when you book the injection itself. It does not apply to the online consultation. Call 951-900-3253 with questions.

Knee Pain Relief

Is PRP Right for Your Knee?

If knee pain from arthritis or wear-and-tear is limiting your walking, stairs, or sleep, platelet-rich plasma (PRP) is one option we use to support joint comfort and function — without jumping straight to surgery.

At Regenerative Medicine at UPC, Dr. Rainier Guiang, MD evaluates whether PRP is a good fit for your knee and goals in a focused cash-pay consult.

Cash-pay note: These regenerative treatments are elective and generally not covered by insurance. We provide a clear plan and pricing before you decide. Superbill available on request.
Indications

Who This Is For

PRP for the knee is most often considered for:

Mild to moderate knee osteoarthritis

Wear-and-tear arthritis that limits walking, stairs or sleep.

Persistent knee pain

Pain that continues after rest, PT, or bracing.

Degenerative or partial meniscus tears

Considered for degenerative or partial tears.Surgical tears are evaluated case by case.

Hoping to delay or avoid knee replacement

Results vary; not a guarantee.

Active adults

Who want a non-opioid, procedure-based option.

Want a candid answer

A focused cash-pay consult with Dr. Guiang on whether PRP fits your knee and goals.

Honest Screening

Who May Not Be a Good Candidate

PRP may not be right if you haveWe’ll tell you if that’s you

  • Advanced “bone-on-bone” arthritis where replacement is already clearly indicated
  • Active infection or certain blood disorders
  • Unrealistic expectation of a permanent “cure” from one injection
  • A locked knee or large displaced meniscus tear Surgical opinion
We’ll be direct in consult if PRP is unlikely to help.

Why patients choose UPC

A physician-led, straight-talking approach:

Physician-performedDr. Guiang evaluates your knee and performs the injection.
Appropriate guidanceInjected into the knee under appropriate guidance, with imaging reviewed if available.
Candid recommendationIf PRP is unlikely to help your knee, we’ll say so.
Plain Language

What PRP Is

PRP uses a concentrated portion of your own platelets, prepared from a blood draw, and injected into the knee under appropriate guidance.

1

Small blood draw

A sample of your own blood is drawn at your procedure visit.

2

Platelets concentrated

The blood is processed to concentrate the platelets.

3

Injected into the knee

Platelets release growth factors that can support the local healing environment.

Good to know: PRP is not a steroid and is not the same as a gel “lubrication” shot.
Learn more on our main PRP & PRF injections for pain page.Read more
Comparing Options

PRP vs Cortisone for the Knee

Cortisone

  • Can calm a flare quickly for some people
  • Relief is often shorter-lived
  • Repeated steroids may not be ideal for cartilage over time

PRP

  • Uses your own platelets — not a steroid
  • Chosen more often when the goal is longer-term comfort and function
  • Results vary by person and severity
PRP vs Cortisone for Knee Arthritis
Realistic Expectations

How Long Does PRP Last?

Study results vary by protocol and severity. Many patients who respond notice meaningful change over weeks, with benefit that can last months — sometimes in the 6–12 month range for knee arthritis in published data, not a promise for every knee.
*Published data for knee arthritis; results vary.

How Long Does PRP Actually Last?

Get a straight answer for your knee

Focused, cash-pay consult with Dr. Guiang.

Step by Step

What to Expect

1

Consult

History, exam, imaging review if available, candid recommendation.

Complimentary
2

Procedure visit

Blood draw, processing, knee injection.

3

Aftercare

Activity pacing; avoid anti-inflammatories if we ask you to; follow-up plan.

Your Physician

Meet Dr. Rainier Guiang, MD

Rainier Guiang, MD, Director of Regenerative Medicine at University Pain Consultants

Rainier Guiang, MD

Director of Regenerative Medicine · University Pain Consultants

Dr. Guiang is board-certified in Anesthesiology and Pain Management (ABA) and leads the Regenerative Medicine program at University Pain Consultants. He personally evaluates whether PRP is a good fit for your knee and goals, and he’ll be direct if it’s unlikely to help.

ABA board-certified Pain medicine specialist Riverside & Menifee
Two Convenient Offices

Locations

Riverside and Menifee, CA — Regenerative Medicine at UPC (University Pain Consultants campus). Regen line: 951-900-3253.

Riverside

6900 Brockton Ave, Suite 203
Riverside, CA 92506

Get directions

Menifee

27990 Sherman Road
Menifee, CA 92585

Get directions

Not sure PRP is right for you? For some tendon and ligament problems, dextrose prolotherapy is another physician-performed, non-surgical injection option offered at both our Riverside and Menifee offices. We'll talk through both at your consult.

What Patients Say on Google

“The procedure went well. Immediately after injection my back felt some relief. Its wonderful to have this relief after 6years of feeling pain. I would definitely endorse him to do this procedure again.”

Patricia H. · Google review

“This was a godsend. I was having back troubles for the past few years and I’ve tried everything from physical therapy to peptides nothing really worked until I got the PRP shot. I’m over a month in and feel like my back…”

Michael M. · Google review

“I had an amazing experience with Dr.Guiang and my PRP (platelet-rich plasma) injection for my knee! I had the procedure done on July 1st, and I’m so happy with the results. I had zero pain afterward and have been feeling amazing ever…”

Yadira R. · Google review

Individual experiences; results vary.

PRP for the Knee — FAQ

Is this the same as the insurance pain clinic?

No. Regenerative Medicine at UPC is our cash-pay regenerative department. Traditional insurance-based pain care is a separate practice, University Pain Consultants.

Can PRP delay a knee replacement?

Sometimes it helps patients stay active longer; it does not replace surgery when structural disease is too advanced. We’ll say so if that’s you.

Can PRP help a meniscus tear?

It may help some people with degenerative or partial meniscus tears, especially when pain persists after rest, PT, or bracing. Results vary, and published evidence is still developing. Some tears need a surgical opinion instead, such as a knee that locks or catches, or a large displaced tear. We review your exam and any MRI at your consult and refer you to an orthopedic surgeon when that is the better path.

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