Regenerative Medicine at UPC · Riverside & Menifee, CA
PRP for Knee Pain in Riverside & Menifee
Platelet-rich plasma (PRP) from your own blood, considered for knee arthritis, wear-and-tear knee pain and meniscus tears — to support joint comfort and function without jumping straight to surgery.
Medically reviewed by Rainier Guiang, MD · Board-certified in Anesthesiology and Pain Management (ABA)

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Save 10% on your PRP injection with code PRP10. Enter the code when you book the injection itself. It does not apply to the online consultation. Call 951-900-3253 with questions.
Is PRP Right for Your Knee?
If knee pain from arthritis or wear-and-tear is limiting your walking, stairs, or sleep, platelet-rich plasma (PRP) is one option we use to support joint comfort and function — without jumping straight to surgery.
At Regenerative Medicine at UPC, Dr. Rainier Guiang, MD evaluates whether PRP is a good fit for your knee and goals in a focused cash-pay consult.
Who This Is For
PRP for the knee is most often considered for:
Mild to moderate knee osteoarthritis
Wear-and-tear arthritis that limits walking, stairs or sleep.
Persistent knee pain
Pain that continues after rest, PT, or bracing.
Degenerative or partial meniscus tears
Considered for degenerative or partial tears.Surgical tears are evaluated case by case.
Hoping to delay or avoid knee replacement
Results vary; not a guarantee.
Active adults
Who want a non-opioid, procedure-based option.
Want a candid answer
A focused cash-pay consult with Dr. Guiang on whether PRP fits your knee and goals.
Who May Not Be a Good Candidate
PRP may not be right if you haveWe’ll tell you if that’s you
- Advanced “bone-on-bone” arthritis where replacement is already clearly indicated
- Active infection or certain blood disorders
- Unrealistic expectation of a permanent “cure” from one injection
- A locked knee or large displaced meniscus tear Surgical opinion
Why patients choose UPC
A physician-led, straight-talking approach:
What PRP Is
PRP uses a concentrated portion of your own platelets, prepared from a blood draw, and injected into the knee under appropriate guidance.
Small blood draw
A sample of your own blood is drawn at your procedure visit.
Platelets concentrated
The blood is processed to concentrate the platelets.
Injected into the knee
Platelets release growth factors that can support the local healing environment.
PRP vs Cortisone for the Knee
Cortisone
- Can calm a flare quickly for some people
- Relief is often shorter-lived
- Repeated steroids may not be ideal for cartilage over time
PRP
- Uses your own platelets — not a steroid
- Chosen more often when the goal is longer-term comfort and function
- Results vary by person and severity
How Long Does PRP Last?
Study results vary by protocol and severity. Many patients who respond notice meaningful change over weeks, with benefit that can last months — sometimes in the 6–12 month range for knee arthritis in published data, not a promise for every knee.
*Published data for knee arthritis; results vary.
Get a straight answer for your knee
Focused, cash-pay consult with Dr. Guiang.
What to Expect
Consult
History, exam, imaging review if available, candid recommendation.
ComplimentaryProcedure visit
Blood draw, processing, knee injection.
Aftercare
Activity pacing; avoid anti-inflammatories if we ask you to; follow-up plan.
Meet Dr. Rainier Guiang, MD
Rainier Guiang, MD
Director of Regenerative Medicine · University Pain Consultants
Dr. Guiang is board-certified in Anesthesiology and Pain Management (ABA) and leads the Regenerative Medicine program at University Pain Consultants. He personally evaluates whether PRP is a good fit for your knee and goals, and he’ll be direct if it’s unlikely to help.
Locations
Riverside and Menifee, CA — Regenerative Medicine at UPC (University Pain Consultants campus). Regen line: 951-900-3253.
Not sure PRP is right for you? For some tendon and ligament problems, dextrose prolotherapy is another physician-performed, non-surgical injection option offered at both our Riverside and Menifee offices. We'll talk through both at your consult.
What Patients Say on Google
“The procedure went well. Immediately after injection my back felt some relief. Its wonderful to have this relief after 6years of feeling pain. I would definitely endorse him to do this procedure again.”
“This was a godsend. I was having back troubles for the past few years and I’ve tried everything from physical therapy to peptides nothing really worked until I got the PRP shot. I’m over a month in and feel like my back…”
“I had an amazing experience with Dr.Guiang and my PRP (platelet-rich plasma) injection for my knee! I had the procedure done on July 1st, and I’m so happy with the results. I had zero pain afterward and have been feeling amazing ever…”
Individual experiences; results vary.
PRP for the Knee — FAQ
Is this the same as the insurance pain clinic?
No. Regenerative Medicine at UPC is our cash-pay regenerative department. Traditional insurance-based pain care is a separate practice, University Pain Consultants.
Can PRP delay a knee replacement?
Sometimes it helps patients stay active longer; it does not replace surgery when structural disease is too advanced. We’ll say so if that’s you.
Can PRP help a meniscus tear?
It may help some people with degenerative or partial meniscus tears, especially when pain persists after rest, PT, or bracing. Results vary, and published evidence is still developing. Some tears need a surgical opinion instead, such as a knee that locks or catches, or a large displaced tear. We review your exam and any MRI at your consult and refer you to an orthopedic surgeon when that is the better path.