Low-dose naltrexone (LDN) may be worth discussing for some adults with fibromyalgia and persistent widespread pain. Dr. Rainier Guiang, MD reviews your symptoms, medications, medical history, and goals in a focused cash-pay consult before deciding whether LDN is a reasonable option in Riverside or Menifee.
Cash-pay note: Regenerative Medicine at UPC is separate from insurance-based pain care. We explain the plan and expected costs before you decide; a superbill is available on request.
Who LDN may be for
- Adults with fibromyalgia or widespread pain who want to review medication options
- People dealing with pain-related sleep, fatigue, or activity limitations
- Patients who can provide a complete medication and health history
- People interested in a cautious, individualized plan with realistic goals
Who may not be a good fit
- Anyone currently taking opioid pain medication without a safe, clinician-guided plan to avoid interactions
- People with significant liver disease or another contraindication that requires a different approach
- Those seeking an instant or guaranteed solution for fibromyalgia
- Anyone who needs urgent assessment for a new or rapidly changing symptom
We will review alternatives and recommend coordination with your current clinician when needed.
What LDN is
Naltrexone is a prescription medication used at different doses for specific medical purposes. “Low dose” describes an individualized dosing approach that some clinicians discuss for chronic pain; use for fibromyalgia is not a promise of benefit and may be considered off-label. Dr. Guiang will explain the reasoning, safety issues, and alternatives before any plan is made.
Read more on our main low-dose naltrexone for pain page.
Can LDN help fibromyalgia?
Some small studies and clinical experiences suggest that certain patients may notice changes in pain or related symptoms, but evidence is limited and responses differ. We use a trial-and-review approach when appropriate, with attention to function, sleep, side effects, and your broader care plan.
What to expect
- Consult ($95, cash-pay) — review of your fibromyalgia symptoms, medications, health history, and goals
- Medication-safety review — special attention to opioid use, liver health, interactions, and alternatives
- Individualized plan if appropriate — instructions are discussed clearly; do not change prescription medicines without guidance
- Follow-up — review of tolerance, symptom changes, and whether continuing makes sense
Locations
Regenerative Medicine at UPC serves Riverside and Menifee, CA. Call 951-900-3253 or email regeneration@unipain.com.
FAQ
Is LDN a guaranteed treatment for fibromyalgia?
No. Fibromyalgia is variable, and LDN may help some patients but not others. We use realistic goals and reassess rather than promise an outcome.
Can I take LDN with an opioid?
Naltrexone can interfere with opioid medicines and may create safety problems. Tell us about every medication you take, and do not stop or change an opioid without guidance from the prescribing clinician.
Is LDN covered by insurance?
This is a cash-pay regenerative consultation and is separate from University Pain Consultants’ insurance-based care at 951-784-7111.
What is the first step?
Book the $95 consult so Dr. Guiang can review whether LDN is medically appropriate and what alternatives should be considered.
Want a medication review focused on your fibromyalgia goals?
Book your $95 consult · Call 951-900-3253 · regeneration@unipain.com
